| Tamil Nadu Public Service Commission (TNPSC) Syllabus
Post Graduate Degree Standard Other Optional Subjects - Click Here
Pharmocology - (Code - 091) |
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Paper - IUnit - I : General Principles Of Pharmacology - History of Pharmacology and its evolution.
- General Introductory pharmacology - Principles of Pharmacokinetics (PCK) Principles of Pharmacodynamics (PD) Drug theropy principles in geriatric and pediatric patients. Principles of drug therapy in pregnancy and lactation.
- General principles of Pharmacogenctics - Heritable factors influencing drugs Alterations in genetic system by drugs.
- Fetal Therapy.
Unit - II : Systemic Pharmacology - Effect of drugs on Cardiovascular system Central and Autonomic nervous system Gastro intestinal system, Genito urinary system Musculo-skeletal system Hematopoietic system
- Drugs influencing immune responses - immunomodulators.
- Pharmacology of autocoids & temperature regulating systems.
- Miscellaneous - Vitamines, Hormones as drugs, Heavy metals and Chelating agents.
Unit - III : Clinical Pharmacology- Drug safety and efficacy
- Primary screening and conduct of drug trials. preclinical trials, Phase I,II, III and IV trials.
- Monitoring of adverse drug reactions and drug interactions.
- Drug monitoring -Therapcutic drug monitoring.
- Rational prescribing and pharmacocconomics.
Unit - IV : Evaluation Of Drugs And Experimental Methods - Both Qualitative And Quantitative Aspects - Elucidation/Evaluation of mechanism of drug action on various systems lic - CNS, CVS, GIT, GUT, endocrine, Respiratory, Immune function, diuresis etc.
- Methods in acute and chromic toxis studies.
- Methods in phytochemistry.
Unit - V : Recent Advances In Pharmacology Top Paper - IIUnit - I : General Principles Of Pharmacology - General Principles of Toxicology of Xcnobiotics, Environmental pollutants and Pharmacocpidemiology.
- General Principles of Clinical Pharmacology.
- Principles of Bioassy and Drug monitoring.
Unit - II : Systemic Pharmacology- Toxicology - Treatment of poisoning /overdose.
- Social Pharmacology & Pharmacoeconomic
Unit - III : Applied Pharmacology- Pharmacology of Infectious diseases (parasitic, fungal, bacterial, viral etc.,)
- Therapy of disease due to chemical, physical, climatic & environmental causes.
- Therapy of dis.due to genetic & constitutional factors.
- Drug therapy in the young and neonate, old patients.
- Drug therapy of neuropsychiatrid syndromes.
- Basic knowledge of anatomy, physiology, biochemistry, Microbiology and pathology, cellular and molecular biology applied to pharmacology.
Unit - IV : Evaluation Of Drugs And Experimental Methods - Both Qualitative And Quantitative Aspects- Biological standardisations - ID50 ED50 etc., in intact and isolated preparations.
- Methods of pharmacokinctics - measurements of PL. conc. Elim t 1/2 vd, AUC, pcak pl conc vs. through conc etc.
- Basic principles of instrumentation PH meter spectrophotometer (UV-Vis & flourescence), Flamcphotometry, Chromatography, HPIC, Electrophores is and use of computers in pharmacology.
Unit - V : Progress In Medicinal Chemistrycurrent Trends |

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